Ongoing Clinical Trial in USA May Lead to Eliminate HIV Virus and AIDS
A new HIV vaccine is being tested in the United States and South Africa. This is the first stage of testing and will check if the vaccine is safe and if it helps the body fight against this virus. The National Institute of Allergy and Infectious Diseases (NIAID) is supporting this research with money and expertise. They’ve been helping with this vaccine idea from the start.
VIR-1388 is a special kind of vaccine that teaches our body to make T cells. These T cells can recognize HIV and tell our immune system to fight it off, stopping it from causing a long-lasting infection. VIR-1388 uses a weakened form of a virus called cytomegalovirus (CMV) to carry the HIV vaccine to our immune system. This doesn’t make people sick in the study. CMV has been around in many people for a very long time. Most people who have it don’t feel sick or even know they have it. CMV stays in the body forever, which means it could be a good way to keep the HIV vaccine in our bodies for a long time, possibly better than other vaccines that don’t last as long.
Since 2004, NIAID, along with the Bill & Melinda Gates Foundation and Vir Biotechnology, has been supporting the development of the CMV vaccine. They are also helping fund this trial. The trial is being led by Vir and carried out through the NIAID-funded HIV Vaccine Trials Network (HVTN) under the name HVTN 142.
HVTN 142 is happening in six places in the United States and four in South Africa. It will include 95 people who do not have this desease. These participants will be randomly put into one of four groups: three groups will get different amounts of the vaccine, and one group will get a fake treatment. To make sure everyone stays safe, this study will only include people who already have CMV but don’t show any symptoms. We expect to see the first results in late 2024. There’s also an optional part of the study that will keep track of volunteers for up to three years after they get their first vaccine shot.
No, there is no widely available vaccine for HIV. Scientists around the world are working hard to develop one, but it’s a complex challenge. They have made progress, and some experimental vaccines are being tested, but none are ready for regular use yet. It’s important to keep practicing safe behaviors to protect against this desease. like using condoms and getting tested regularly if you’re at risk. Always consult a healthcare professional for the most up-to-date information on HIV prevention and treatment.
Is HIV vaccine available in India?
No, there is no Vaccine available in India. Some trials are running in different stages in different countries , but all of them are in testing phase.
When was the first HIV vaccine trial started ?
The first vaccine trial, known as the VaxGen trial, began in 1998. This trial tested a vaccine called AIDSVAX, but unfortunately, it did not provide significant protection against this Since then, there have been numerous other vaccine trials conducted in the pursuit of finding an effective vaccine.
What is HIV vaccine used for?
An HIV vaccine is designed to stimulate the immune system to produce antibodies and T cells that can recognize and fight this virus. It aims to prevent or control infection, ultimately reducing the risk of developing AIDS. While an effective HIV vaccine would be a critical tool in the global fight against AIDS, a widely accessible and effective vaccine has not yet been developed. Research in this field continues, with the hope of one day achieving this significant milestone in the prevention and public health.
Are we close to a cure for HIV?
Significant progress has been made in this research, but a complete cure for this has not yet been achieved. While antiretroviral therapy (ART) effectively controls the virus, it doesn’t eradicate it from the body. Promising strategies, like gene editing and long-acting therapies, show potential, but more research is needed. Achieving a complete cure remains a complex challenge. Regular testing, early treatment, and safe behaviors remain crucial in managing HIV. Consult healthcare professionals for the latest updates on AIDS treatments and research, and continue to follow recommended prevention measures.
What is the new research on HIV virus?
Recent research has focused on several key areas. One promising avenue involves long-acting treatments, which aim to reduce the frequency of medication intake. This could enhance adherence and effectiveness. Gene editing techniques, like CRISPR, are being explored to potentially modify immune cells to resist this infection. Another area of interest is broadly neutralizing antibodies, which have shown promise in preventing and controlling AIDS. Novel vaccine candidates, like VIR-1388, are being tested for their ability to stimulate immune responses against the virus. Additionally, efforts are underway to develop a functional cure, aiming to control the virus without the need for lifelong medication. Despite these advancements, a complete cure for HIV remains a complex challenge, and regular testing, early treatment, and safe practices remain critical in managing the virus. It’s important to note that the field of HIV research is dynamic, and staying updated through reliable healthcare sources is crucial for the latest developments. Always consult healthcare professionals for the most current information on HIV prevention and treatment.
1 thought on “HIV Vaccine Clinical Trials in 2023”
1 thought on “HIV Vaccine Clinical Trials in 2023”